World’s End Harem is an ec science fiction manga series created by Kotaro Shono, with LINK as the writer and illustrator. The series is set to receive an anime adaptation in 2021, and the main cast of characters has been officially unveiled. Notably, the majority of these characters are female.
The story of World’s End Harem is set in a world that has been ravaged by the MK Virus, known as the “Man Killer” virus, which has led to the demise of all males on Earth. However, Reito Mizuhara is one of the rare few men in Japan who have developed immunity to this deadly virus.
In a bid to ensure the survival of humanity, Reito is compelled to participate in a reproduction program. While navigating the mysteries surrounding the MK Virus, he is also determined to find his girlfriend, Elisa, who has mysteriously disappeared.
Without further delay, here are the primary characters from World’s End Harem, along with their respective designs and voice actors:
Reito Mizuhara (CV: Taichi Ichikawa)
Reito Mizuhara, voiced by Taichi Ichikawa, stands at the center of the World’s End Harem story as its main protagonist.
Before the global collapse, Reito was a brilliant medical student whose promising future was put on hold when he was diagnosed with a rare and incurable condition known as cellular sclerosis. To preserve his life, he agreed to undergo cryogenic sleep until medical advancements could offer him a cure.
When he awakens five years later, Reito discovers a completely changed world: the Male Killer (MK) virus has devastated humanity, eradicating 99.9% of the male population and leaving society almost entirely female. As one of only five surviving men in Japan, dubbed the “Numbers,” he is thrust into the role of a potential savior—tasked with fathering the next generation to ensure the survival of humankind.
Yet, Reito is far from willing to become just a breeding tool for the female-led government, known as the United Women (UW). His motivations diverge from the expectations placed upon him. Guided by his intelligence, integrity, and moral strength, he dedicates himself to two goals:
- Finding a cure for the MK virus to restore balance to humanity.
- Reuniting with Erisa Tachibana, his childhood friend and unspoken love, who mysteriously vanished during his years in cryosleep.

Mira Suo (CV: Haruka Shiraishi)
Mira Suo, voiced by Haruka Shiraishi, is one of the most enigmatic and pivotal female characters in World’s End Harem.
At first glance, Mira is introduced as the exclusive attendant and bodyguard assigned to protagonist Reito Mizuhara. Her duty, as dictated by the United Women (UW), is to protect him, oversee his daily life, and assist in his government-assigned mission of “mating” to restore the human population. To Reito and those around her, Mira initially appears to be calm, composed, and detached, carrying out her responsibilities with clinical precision.
Beneath this professional facade, however, Mira proves to be far more complex. She demonstrates remarkable combat skills and a quiet intensity that hints at a concealed history. Her character arc gradually peels back layers of mystery, raising questions about her true loyalties and hidden agenda within the UW’s operations.
A defining element of Mira’s role in the story is her uncanny resemblance to Erisa Tachibana, Reito’s childhood friend and lost love. This resemblance unsettles Reito and creates a nuanced tension between them, blurring the line between professional duty and personal emotion. Is Mira simply a tool of the UW, or does her resemblance to Erisa signal something deeper, perhaps even intentional, about her origins?

Akane Ryuzoji (CV: Yo Taichi)
Akane Ryuzoji, voiced by Yo Taichi, is a notable supporting character in World’s End Harem.
When protagonist Reito Mizuhara awakens from cryogenic sleep, Akane is one of the first women he encounters. A skilled nurse at the UW medical facility, she plays both a professional and highly personal role in Reito’s new life. As part of the government’s repopulation project, Akane is among the initial candidates chosen to become Reito’s partner.
Akane is characterized by her mature beauty, confidence, and overt sensuality. Unlike many others who attempt subtle approaches, she is direct and unapologetic in expressing her desires, often teasing or seducing Reito in hopes of drawing his affection. Her assertiveness makes her stand out among the many women vying for the attention of the surviving men.

Sui Yamada (CV: Aya Yamane)

Kamiya Karen (CV: Ayana Taketatsu)

Shota Doi (CV: Kazuki Ura)

Yuzuki Hanyu (CV: Marika Hayase)

Akira Todo (CV: Riho Iida)
Akira Todo, voiced by Riho Iida, is a supporting yet significant character in the anime series World’s End Harem. She serves as a researcher and medical specialist working under the United Women (UW) Japan Branch, playing a pivotal role in the survival project following the outbreak of the Male Killer (MK) virus.
When Reito Mizuhara, the series’ protagonist, awakens from cryosleep, Akira is assigned as his personal medical attendant. Her primary duties involve closely monitoring his physical condition and ensuring he remains healthy throughout his time in UW custody. She also oversees the controversial “repopulation project,” which tasks surviving men with fathering children to secure humanity’s future.
Akira is characterized by her calm, professional demeanor and her dedication to her work. Though she often comes across as serious and composed, her interactions with Reito reveal her compassionate side, showing that she genuinely cares about his well-being beyond mere duty.
Unlike some other characters involved in the project, Akira balances the scientific and ethical responsibilities of her position, making her one of the more grounded figures within the UW organization.

Chifuyu Rehn Kuroda (CV: Natsumi Takamori)
Chifuyu is one of the classmates of Shōta Doi, one of the rare male survivors of the devastating MK (Male Killer) virus. Unlike many of the other women surrounding Shōta, Chifuyu is defined by her petite, childlike appearance, which serves as both her most distinctive trait and her greatest source of insecurity.
Because of her youthful looks, Chifuyu often feels overshadowed by the more mature women vying for Shōta’s attention. While she harbors genuine feelings for him, her frustrations grow when he overlooks her in favor of others. This dynamic sparks moments of jealousy and rivalry, pushing her to prove her worth and claim a place in Shōta’s heart.
Despite her occasional abrasive or competitive behavior, Chifuyu’s emotions come from a place of sincerity. Beneath the envy lies a deep desire to be acknowledged not just as a classmate, but as a woman with her own capacity for love and intimacy. Her vulnerability, mixed with her determination, makes her one of the more emotionally complex figures in Shōta’s storyline.

Shunka Hiiragi (CV: Haruka Miichi)
Shunka Hiiragi, voiced by Haruka Miichi, is one of the memorable supporting characters in the anime and manga series World’s End Harem. She is introduced as a classmate of Shōta Doi, one of the few surviving men in a world devastated by the MK Virus—a mysterious disease that wiped out the majority of the male population.
What makes Hiiragi stand out among the cast is her unmistakable otaku spirit. A devoted fan of anime and idols, she often loses herself in her hobbies to the point of being unaware of what’s happening around her. This quirky obsession brings humor and lightness to the otherwise dark, post-apocalyptic narrative.
Beneath her eccentric interests, however, Shunka reveals a far more compassionate and loyal side. She becomes one of Shōta’s lovers, supporting him while he grapples with both the responsibilities and temptations that come with being one of the last surviving men. In a society where women fiercely compete for scarce male partners, Shunka’s genuine affection and easygoing personality help balance the tension.